ResearchRandomized Controlled Trials
New research:
- 「ヘルシーキャンパストライアル(C1357)におけるスマートフォン認知行動療法アプリの使用と効果に影響する因子の検討」からオプトアウトが可能です 情報公開文書
Completed researches:
- Mindfulness-based therapy for atopic dermatitis: a randomized trial (Ms Kishimoto) [Completed ] Trial homepage

- Smartphone CBT for university students at risk: a fully factorial trial (with Kyoto University Health Service) [Completed]


- Electronic Health Record-nested practical randomized controlled trials [Completed] Protocol
- Smartphone CBT for survivors of breast cancer: a randomized trial (with Nagoya City University) [Completed and published]
A pragmatic mega-trial to establish optimum treatment strategies of new generation antidepressants for major depression [SUN(^_^)D trial]- PROTOCOL: Furukawa TA, Akechi T, Shimodera S, Yamada M, Miki K, Watanabe N, Inagaki M & Yonemoto N (2011) Strategic Use of New generation antidepressants for Depression: SUN(^_^)D study protocol. Trials, 12, 116.
- UPDATED PROTOCOL & STATISTICAL ANALYSIS PLAN: Yonemoto N, Tanaka S, Furukawa TA, Kato T, Mantani A, Ogawa Y, Tajika A, Takeshima N, Hayasaka Y, Shinohara A, Miki K, Inagaki M, Shimodera S, Akechi T, Yamada M, Watanabe N & Guyatt GH (2015) Strategic Use of New generation antidepressants for Depression: SUN(^_^)D protocol update and statistical analysis plan. Trials, 16, 459.
- PRIMARY RESULTS: Kato T, Furukawa TA, Mantani A, Kurata K, Kubouchi H, Hirota S, Sato H, Sugishita K, Chino B, Itoh K, Ikeda Y, Shinagawa Y, Kondo M, Okamoto Y, Fujita H, Suga M, Yasumoto S, Tsujino N, Inoue T, Fujise N, Akechi T, Yamada M, Shimodera S, Watanabe N, Inagaki M, Miki K, Ogawa Y, Takeshima N, Hayasaka Y, Tajika A, Shinohara K, Yonemoto N, Tanaka S, Zhou Q, Guyatt GH & for the SUN(^_^)D Investigators (2018) Optimising first- and second-line treatment strategies for untreated major depressive disorder - the SUND study: a pragmatic, multi-centre, assessor-blinded randomised controlled trial. BMC Medicine, 16, 103.
- Adding smartphone-based cognitive-behaviour therapy to pharmacotherapy for major depression [FLATT trial]
- PROTOCOL: Watanabe N, Horikoshi M, Yamada M, Shimodera S, Akechi T, Miki K, Inagaki M, Yonemoto N, Imai H, Tajika A, Ogawa Y, Takeshima N, Hayasaka Y, Furukawa TA, Steering Committee of the Fun to Learn to A & Think through Technology P (2015) Adding smartphone-based cognitive-behavior therapy to pharmacotherapy for major depression (FLATT project): study protocol for a randomized controlled trial. Trials, 16, 293.
- PRIMARY RESULTS: Mantani A, Kato T, Furukawa TA, Horikoshi M, Imai H, Hiroe T, Chino B, Funayama T, Yonemoto N, Zhou Q & Kawanishi N (2017) Smartphone Cognitive Behavioral Therapy as an Adjunct to Pharmacotherapy for Refractory Depression: Randomized Controlled Trial. Journal of Medical Internet Research, 19, e373.
- ADDITIONAL ANALYSES: Furukawa TA, Horikoshi M, Fujita H, Tsujino N, Jinnin R, Kako Y, Ogawa S, Sato H, Kitagawa N, Shinagawa Y, Ikeda Y, Imai H, Tajika A, Ogawa Y, Akechi T, Yamada M, Shimodera S, Watanabe N, Inagaki M & Hasegawa A (2018) Cognitive and behavioral skills exercises completed by patients with major depression during smartphone cognitive behavioral therapy: Secondary analysis of a randomized controlled trial. JMIR Ment Health, 5, e4.
- A mindfulness-based stress management program and treatment with omega-3 fatty acids to maintain a healthy mental state in hospital nurses [Happy Nurse Project]
- Impact of spin in abstract conclusion on doctors' choices: a randomized trial [DOCTOR study] (Dr Shinohara)
CBT for irritable bowel syndrome (Dr Kikuchi) [Completed and published] Trial homepage




